Why do people use Hydergine?
People who self-experiment with Hydergine often state they use it to improve their:
There is a lack of solid scientific evidence for the effectiveness of Hydergine for any of these purposes, especially in healthy humans.
How does it feel when you take Hydergine?
The following qualitative user experience reports and reviews are included to give you an understanding of what the experience of taking Hydergine is like.
Anecdotal hydergine experience reports and reviews from Reddit
One person said the following about their use of Hydergine:
"I've used Hydergine for over 20 years [...] seems to improve my mental acuity." [8]
Another redditor said the following:
"... it made whatever I was doing feel extremely important. I remember looking at leaves on a bush and thinking how significant it was that I was able to see them. It wasn’t the same sense of focus I get from stimulants, and I didn’t feel compelled to continue doing any one thing in particular, but anything I did gained that same sense of importance." [9]
A third person said the following on Reddit:
"The first two days of using were pretty hectic despite the fact I didn't really feel anything dramatic except for a slight improvement in my visual perception. Also it caused a mild case of nausea and occasional drowsiness which ultimately forced me to sleep the second day of use approximately 4 hours, during the day – that is while listening to music (which by the way sounded radically different, I think the substance made me feel somewhat high). Anyway, fortunately enough I didn't have much to do that day.
However much non pleasing the side effects were, I decided for some reason that I really liked the effects of Hydergine – in particular its virtue of providing a subtle control over ones emotions; also primarily due to its capability of manufacturing a well-being feeling. Day three, I took 3mg in the morning on an empty stomach, and to counter any state of drowsiness I instantly had a caffeine pill (200mg) ready for that, which much to my surprise, did synergize greatly with Hydergine. Frankly, afterwards, I never felt that energetic in months. It was as if I had a massive adrenaline rush that drastically improved my mood and provided me with an utmost drive of motivation a body seeks for. I was ready to start doing anything. ANYTHING. I never felt that prepared - mentally and physically - in years. Plus I didn't encounter the side effects which I had the first two days during my trial; perhaps the only downside I could think of (isn't bad actually) was the excessive amount of drive that had me wanting to go out and start a random fight with random strangers - a friendly fight, that is. Yes, mood was awesome." [10]
Yet another redditor had:
"Headaches and then a subtle shift to a more hedonistic approach to life. Sounds funny, but that's what I got from it." [11]
And another person said:
"I took 9mg once while I was doing scientific research and came up with a breakthrough idea, after about an hour an a half of being very nauseated on the verge of emesis (it was the worse drug side effect I have ever experienced*)." [12]
Should you use Hydergine?
One thing that is certain about the effects of Hydergine is that we know relatively little about them. There is a lack of high-quality research, especially in healthy humans.
Because of the lack of research on Hydergine, we never recommend that people use it.
If you have already decided to use it, here are some guidelines to maximize the benefits and minimize the risks.
How much and how often should you dose Hydergine?
Human studies in people with cognitive impairment tend to use doses between 1 and 9mg Hydergine, divided into three doses per day. It is usually taken daily.
What substances may stack well with Hydergine?
There's no high-quality research on the effects of combining Hydergine with other substances, such as nootropic drugs or supplements. The safety and efficacy of the below-listed combinations are supported only by anecdotal reports.
People tend to report better effects from Hydergine when they also use:
Before combining any drugs or supplements, talk with your trusted medical professional about the risks involved.